Carodyl Injection

Carodyl injection contains carprofen 5% w/v. Carprofen preferentially inhibits the COX-2 enzyme and limits the production of prostaglandins involved in the inflammation. It is an NSAID of the propionic acid class that includes ibuprofen, ketoprofen, etc. Metabolism of carprofen takes place in the liver and excreted in bile.

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Description

Carodyl Injection

Brand Name: Carodyl Injection

Manufactured by: SAVA VET / SAVA Healthcare Limited

Doses form: Injection

Presentation: 

20 ml

Ingredients & Composition:

Each ml of Carodyl injection contains

Carprofen IP                         50 mg
Benzoyl alcohol IP               1.04% w/v (as preservative)
Water for injection IP          q.s.

Description / Action: 

Carodyl injection contains carprofen 5% w/v. Carprofen preferentially inhibits the COX-2 enzyme and limits the production of prostaglandins involved in the inflammation. It is an NSAID of the propionic acid class that includes ibuprofen, ketoprofen, etc. Metabolism of carprofen takes place in the liver and excreted in bile.

Class: NSAID (Non-steroidal anti-inflammatory drugs) 

Indication / Uses:

Carodyl injection is indicated in the dogs for

  • Treatment and relief of pain and inflammation associated with osteoarthritis
  • To control postoperative pain associated with soft tissue.
  • Control of postoperative pain associated with orthopaedic surgeries in dogs.

Dosage and administration:

The recommended dosage for subcutaneous administration for dogs is 4 mg/kg of body weight daily i.e. 1 ml / 12.5 kg.

The total dose may be administered as either 4 mg/kg of the body weight once daily or divided and administered as 2 mg/kg bodyweight twice daily.

For the control of postoperative pain, administer approximately two hours before the procedure.

It is for subcutaneous administration only.

Overdoses / Side effects / Contraindications /Warnings:

Overdose may result into serious side effects and GI signs like vomiting, diarrhoea, faecal occult blood, dark or tarry stools, loss of appetite. Gastrointestinal signs may occur after the administration of carprofen like other NSAIDs. Stop the therapy if this persists beyond 1 or 2 days.

Do not use in dehydrated, hypovolemic or hypotensive patients or those who are having GI disease or blood clotting abnormalities.

Do not use carprofen in combination with steroids. At least keep 24 hours gap as they are more potent ulcerogenic when used concurrently.

Pet owners should be warned and informed about possible side effects/ adverse reactions like increased urination, increased water consumption, anaemia (pale gums), jaundice (yellowish gums, skin or conjunctival mucous membranes), lethargy, seizures, incoordination, and behavioural changes so that can be reported on time.

Pharmaceutical precautions / Instructions: 

Store in a cool and dry place at room temperature below 25°C. Protect from light. Once broached, the product may be stored at temperatures up to 25°C for 28 days. Following the withdrawal of the first dose, use the remainder within 28 days. Strictly for veterinary use.

Safety: Age / Pregnancy/ Withdrawal:

Do not use in case of hypersensitivity to any active substance or excipients. Do not use in dogs having cardiac, renal or hepatic issues. Age-specific restrictions, safety for breeding and lactating animals have not been instructed.

Always follow the recommended dose. It has no reported withdrawal side effects.

Habit forming:  No

Substitute: Carpade Injection

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