Description

Cortavance Hydrocortisone Spray

Manufactured by: Virbac

Dosage form: Spray

Presentation: 

Spray Bottle of 76 ml

Ingredients & Composition:

Active ingredients of Cortavance Spray:

Hydrocortisone aceponate 0.584 mg/ml

Description / Action: 

Cortavance is the cutaneous hydrocortisone spray for dogs and cats. Hydrocortisone aceponate is a di-ester of Hydrocortisone that makes all the difference. Lipophilic properties, affinity for the skin helps in rapid penetration in the skin. It has reservoir effect in the skin which helps in the storage in superficial dermis. Along with an initial parasiticide application or use, Cortavance spray rapidly improves the resolution of Flea Allergy Dermatitis (FAD) in dogs.

Class: Topical Corticosteroid

Indication / Uses:

• Pyotraumatic dermatitis
• Flea allergic dermatitis (FAD)
• Contact allergy
• Lick dermatitis
• Perianal fistulae
• Pododermatitis
• Cutaneous lupus
• Pemphigus foliaceus
• Atopic dermatitis
• To control inflammation and pruritus

 Dosage and administration:

2 pump spray per 10 cm x 10 cm of body surface area.

Keep 10 cm distance from the body surface while spraying.

(No massage required, cover eyes when spraying face).

Frequency: Once daily

Route: Topical / External – Directly on dog skin lesions

Species: For topical use Dogs, Cats, Exotic pets (Rabbits, ferrets), Horses

Duration: 7 days (Hydrocortisone aceponate spray is safe and effective up to 70 days in the management of canine atopic dermatitis)

Over-dosage / Side effects / Contraindications /Warnings:

Do not treat more than 1/3 of the pet’s total skin surface. Use of hydrocortisone is not recommended in case of severe lesions and pyoderma. Specific biotransformation in the skin provides enhanced efficacy without the side-effects associated with glucocorticosteroids.

Pharmaceutical precautions / Instructions: 

Store below 25°C in a dry place or at room temperature. Not for use in humans. Strictly for veterinary use. Keep reach out of the children.

Safety: Age / Pregnancy/ Withdrawal:

Prolonged use of upto 70 days in study trials there was no abnormalities in haematological and biochemical parameters. Pre and post ACTH cortisol levels remains within normal range during the extended use of hydrocortisone. The immune system remains untouched & unthreatened.

Hydrocortisone aceponate has 60 time greater potency than Hydrocortisone yet none of the side-effects of typical corticosteroids.

Topical Steroid	Blood Absorption Level	Relative Skin Absorption Level	Relative Potency	Systemic Effects
Hydrocortisone Aceponate (HCA)	Non-systemic	Rapid	5/5	Negligible
Prednisolone	Systemic	Slow	2/5	Yes 3/5
Betamethasone	Systemic	Slow	5/5	Yes 5/5
Hydrocortisone	Systemic	Slow	1/5	Yes 1/5

(Relative potency of hydrocortisone is based on control of inflammation & pruritus)

It has no systemic impact and does not cause cutaneous atrophy.

Safety for use in breeding / lactating or pregnant animals has not been established.

Substitute: Prurigo Spray, Pjjes Spray, Hartz hydrocortisone spray, Excel hydrocortisone spray,