Description

Canglob D Forte

Brand Name: Canglob D Forte

(Heterologous distemper virus immunoglobulins/antibodies for dogs)

Manufactured by: Dyntec Spol S.R.O.

Dosage form: Injection (Suspension)

Presentation: 

1 x 6 ml, 1 x 5 ml, 6 x 5 ml

All sizes may not be available / marketed.

Ingredients & Composition:

Each 1.0 ml of Canglob D Forte contains:

Canine Distemper virus immunoglobulins/antibodies NLT 320 VNAb₅₀

(VNAb – Titre of virus-neutralization antibodies in a sample dilution, when 50% of cytopathic changes evoked by the virus in a given work dose are subdued)

Excipients:

Thiomersal NMT 0.1 mg,

Diluting medium 1.0 ml.

Description / Action: 

Canglob D Forte is a liquid suspension containing purified hyperimmune immunoglobulins/antibodies (IgY) against canine distemper to ensure passive immunization of dogs, for therapeutic / treatment and prophylactic use. Disease/virus / pathogen-specific antibodies facilitate to prevent the development of disease or if they already run – to alleviate its course.

Class: Biologicals / Dog / Distemper immunoglobulins

Indication / Uses:

Canglob D Forte is indicated for passive immunization against canine distemper virus infection

• Treatment / Therapeutic
• Prophylaxis

They are used to provide passive immunity in animals, for which active immunization is not suitable, mostly in weakened animals, before transfers and exposure to various other stress factors.

Dosage and administration:

0.4 ml/kg body weight (irrespective of breed, age, and sex).

Canglob D Forte suspension/distemper virus antibodies should be administered intravenously / intramuscularly or subcutaneously.

Therapeutic dosage should be administered daily until improvement of the health status (it may be used in ill animals).

The preventive/prophylactic dose is 0.4 ml/kg of body weight given at 5-day intervals (it may be used in cases of an immediate endangerment by a disease).

The highest daily dose is 0.4 ml/kg of body weight, which may be used both for therapy and prophylaxis.

The length of therapy of the prophylactic protection and the route of administration should be assessed by a veterinarian.

Onset and Duration of immunity:

Dose 0.4 ml/kg of body weight stimulates passive immunity for a period of approximately 5 days.

Passive immunity develops in dependence on a route of administration. Its duration is dependent on the amount of the product administered as well as on the frequency of replications of the administration. On intravenous administration, immediate onset of the passive immunity is recorded. But the utilization of immunoglobulins is the highest. After intramuscular and subcutaneous administration, a slightly delayed onset of the passive immunity is recorded as well as immunity being lowered as compared with the i.v. administration.

Overdoses / Side effects / Contraindications /Warnings:

Do not use for prophylactic use in sensitized animals or on the onset of allergic and anaphylactic reactions in cases of repeated utilization.

Active immunization against infectious agents contained in the product is recommended 7 days after the last administration.

Pharmaceutical precautions / Instructions: 

Store between 2 °C and 8 °C. Do not freeze.  For animal treatment only. Veterinary medicinal product to be supplied only on veterinary prescription.

Safety: Age / Pregnancy/ Withdrawal:

Age-related safety and use in pregnant and lactating bitches have not been stated by the manufacturer.

Substitute: Updating Soon

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