Description

Wigepsy 500 mg Tablets

Levetiracetam Tablets For oral use in Dogs & Cats Only

Manufactured/Mktd by: Wiggles / Sixth Sense Retail Pvt. Ltd.

Dosage form: Tablets

Presentation: 

1X10 Pack

Ingredients & Composition:

Each film-coated tablet contains:

Levetiracetam IP                  500 mg
Excipients                            q.s.
Colour: Yellow oxide of Iron & Titanium Dioxide IP

Description: 

Wigepsy 500 mg Tablets contain Levetiracetam that belongs to the Pyrrolidine class. It is effective in the treatment of various types of seizures (fits) in dogs and cats resulting from epileptic disorders.

Mechanism Of Action:

The mechanism by which Levetiracetam exerts its antiepileptic effects are not clearly defined. It is thought that binding to the distinct protein synaptic vesicle protein 2A serves as the most important mechanism of action (SV2A). SV2A protein is a part of secretory vesicle membranes that mediate calcium-dependent vesicular neurotransmitter release. The binding of LEV to SV2A appears to decrease the rate of vesicle release.

While having no direct impact on GABAergic or glutamatergic receptors, levetiracetam has also been found to indirectly influence GABAergic neurotransmission and regulate ionic currents. Levetiracetam has also been demonstrated to block N-type calcium channels in vitro. It is yet unclear how, or even if, these activities contribute to its anti-epileptic activity.

Class: Anti-epileptic/ Anti-convulsant

Indication / Usage:

• Seizures & Epilepsy

• Treats partial, myoclonic, & tonic-clonic fits

* Dogs and cats with epilepsy experience seizures that can be challenging to manage. A single medicine is usually insufficient to control the problem.

* This prescription anticonvulsant medicine levetiracetam is used with other drugs to treat seizures caused by epilepsy. Levetiracetam aids in the treatment of epilepsy and improves the quality of life for your pet when used in conjunction with phenobarbital and bromides. Moreover, hepatic encephalopathy-related seizures can be controlled by levetiracetam.

Dosage and administration:

10 – 30 mg/kg body weight
Or As directed by the Veterinarian

Levetiracetam tablets have been developed for oral administration with high palatability. Tablets may be given directly by mouth or offered in a small amount of food. Fasting is neither necessary nor recommended prior to or after treatment.

Features:

Easy to use
Fast action
Vet approved

Overdoses / Side effects / Contraindications /Warnings:

Levetiracetam should be used with caution in animals with decreased kidney function. There may need to be dose and dosage frequency adjustments. In order to prevent the likelihood of withdrawal seizures, a gradual withdrawal from levetiracetam is advised.

The most common side effects include sleepiness and incoordination in dogs. In cats, a decreased appetite, incoordination, drooling, and sleepiness occur most commonly. Serious side effects include persistent vomiting or sudden changes in behavior. This short-acting medication should stop working within 24 hours, although effects can be longer in pets with liver or kidney disease.

Do not use this medication in pets that are allergic to it. Use cautiously in pets with kidney disease, or pets that are pregnant or nursing.

The following medications should be used with caution when given with levetiracetam: carbamazepine, central nervous system depressants, methotrexate, nonsteroidal anti-inflammatory drugs (NSAIDs), or phenobarbital.

Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking.

Withdrawal:

Sudden discontinuation of the drug may result in withdrawal seizures.

Safety: Age / Pregnancy/ Withdrawal:

Not recommended for use in pregnant and lactating female dogs and cats.

Pharmaceutical precautions / Instructions: 

Store protected from sunlight & moisture, at a temperature not exceeding 30°C. Veterinary. Not for human use. For treatment of animals only.

Keep all medicines out of reach of children.

Schedule ‘H’ Prescription Drug Caution: Not to be sold by retailer without the prescription: of a Registered Veterinary Practitioner.

Substitute: Vetina Levetiracetam 500 mg Tablets,