Ursopet Tablets
Ursopet Tablets contain ursodeoxycholic acid. It is a secondary bile acid used for hepatobiliary affections in dogs and cats.
Description
Ursopet Tablets
Ursodeoxycholic Acid for Dogs and Cats
A simple solution for hepatobiliary disorders
Manufactured by: Vivaldis Animal Health
Dosage form: Tablets
Presentation:
A box containing 10 strips of 10 tablets each
Ingredients & Composition:
Each uncoated tablet contains
Ursodeoxycholic acid IP 300 mg
Excipients q.s.
Description / Action:
Ursopet Tablets contain ursodeoxycholic acid. It is a secondary bile acid used for hepatobiliary affections in dogs and cats.
Pathophysiology of Liver Disorders
↑ Cell Damage
↑ Inflammation
↑ Inflammation of biliary duct
Slow bile movement through biliary system
Gall stones + Sludged bile
Bile acid profile becomes hydrophobic
↑ Viscosity of bile
Slow bile movement through biliary system
Gall stones + Sludged bile
↓ Bile acid secretion from hepatic cells
↑ Bile acid concentration in hepatocytes, Causes toxicity
↓ Uptake of bile acid by hepatic cells from blood
↑ Circulatory bile acid levels
Metabolic and pathological changes in heart
Class: Hydrophilic Bile Acid
Indication / Uses:
• Chronic hepatitis
• Idiopathic hepatic lipidosis
• Cholestasis
• Cholecystitis
• Cholangitis
• Sludged bile and cholelithiasis
Benefits of UDCA:
• UDCA is a hydrophilic bile acid present in very small amounts in bile.
• Improves composition of bile acid pool.
• Protects hepatocytes from damage.
• Improves viscosity of bile
• Reduces gall bladder stones and their occurrence
Role of UDCA and mechanisms of action
• Immune modulation
• Alterations of bile acid pool
• Anti inflammatory
• Cytoprotection
• Anti apoptotic
• Cholelith dissolution
• Mitochondrial integrity
• Choleretic
Dosage and administration:
15 mg/kg/day
Dose can be given in up to 2 divided doses per day.
Route: For Oral administration only.
Species: In Dogs and Cats.
Over-dosage / Side effects / Contraindications /Warnings:
May bind with aluminium containing antacids. Do not use in pets with biliary duct obstructions.
Pharmaceutical precautions / Instructions:
Store in a cool and dry place at room temperature. Not for use in humans. Strictly for veterinary use. Keep reach out of the animals and children.
Not to be sold in retail without a prescription of a registered veterinary practitioner.
Safety: Age / Pregnancy/ Withdrawal:
Safe for use in young/ adult/ aged cats and dogs. Not for use in pregnant and lactating female dogs and cats.
Substitute: Pooch Liv-Guard Tablets, Suspension Galibor, Suspension Ursofalk, Ursovet Oral suspension,
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