Description

Ketopet Tablets

Ketopet 200 mg

Ketoconazole Tablets for Dogs and Cats

Manufactured / Marketed by: Sihil Animal Health

Country of Origin: India

Dosage Form: Tablets

Presentation: 

Tablets: 10x1x10 Tablets

Ingredients & Composition:

Each uncoated Tab contains
Ketoconazole IP 200 mg.

Description / Action: 

Ketopet Tablets contain ketoconazole which is an Anti-fungal, Anti androgen, and anti-glucocorticoid used to treat a number of fungal infections. It is an antifungal medication that works well against fungal infections of the skin, respiratory tract, lymph nodes, nails, and bones, among other body regions.

Pharmacodynamics:

Ketopet is a potent inhibitor of ergosterol synthesis which is a main membrane lipid of fungi. This makes it difficult for the Plasma membrane to maintain its integrity leading to fungal cell wall damage. It is also particularly successful in treating Cushing Syndrome since it prevents the adrenal glands from synthesizing cortisone.

Class: Antifungal

Indication / Usage:

Ketoconazole is prescribed for ringworm, fungal ear infections, or skin infections.

Veterinarians also prescribe this antifungal to treat more serious infections, such as cryptococcosis, coccidiomycosis (Valley Fever). and blastomycosis.

In severe cases, it penetrates and affects vital organs including Lung, bones, and nervous system. The duration of treatment for these serious, systemic fungal diseases can be quite long according to the severity of infection, in some cases up to a year in some animals, suppressive treatment can continue for life.

When ketoconazole is used to treat dermatitis due to Malassezia pachydermatitis it is generally used with topical anti-mycotic shampoos.

Two to four weeks of treatment can be necessary for chronic cases. Ketoconazole can be used to treat adrenal hypercorticism in dogs.

In Cushing’s Disease, Ketopet suppresses excessive production of Cortisone hormone synthesis.

Dosage/ Administration:

10 mg/kg bwt once daily for min of 4-6 weeks or as directed by the Veterinarian.

Directions for Use:

Ketopet should be given along with food rich in fatty acids which helps in more absorption Side effects: Ketopet is not recommended in Felines. The most common side effects attributed to ketoconazole administration include gastrointestinal effects such as vomiting, lack of appetite, and diarrhea. More severe side effects of Ketoconazole include increased liver enzyme levels.

It can be used along with immuno-modulatory drugs like Cyclosporin to reduce the dose of it.

Targeted Species:

Dogs and Cats

Overdosage / Side effects / Contraindications /Warnings:

It should be used cautiously in pets with liver disease, low platelet counts, or those that are undergoing stressful events such as serious illness, surgery, or trauma.

The main advantage of Ketoconazole over Amphotericin B is its free from renal side effects. When it is used in the long term monitor the liver enzymes periodically.

Safety/ Pregnancy/ Age:

Ketoconazole should not be used in pregnant, lactating pets and puppies less than 6 months of age.

Pharmaceutical precautions / Instructions: 

Keep in a cool dry and dark place at room temperature. Keep the medicine away from children. Not for human use. For animal treatment only.

Substitute: K-pet Tablets, Petorak-K Tablets,