Phos-clear Powder

Phos-clear is for the management of phosphatemia or increased serum phosphorus levels in dogs and cats suffering from chronic kidney disease or CKD. Persistent hyperphosphatemia along with calcitriol deficiency leads to secondary hyperparathyroidism. Phos-clear helps to control hyperphosphatemia by reducing phosphorus absorption from the intestine hence plays its part in controlling the development of secondary hyperparathyroidism.

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Description

Phos-clear Powder

Brand Name: Phos-clear Powder

Manufactured by: Vivaldis Animal Health ⎥ Vivaldis Health and Foods Pvt. Ltd.

Dosage form: Powder

Presentation: 

35 gm Box with Measuring Spoon

Ingredients & Composition:

Active ingredients per level scoop of Phos-clear powder:
Aluminium hydroxide gel dried and powdered                          250 mg
(100% pure and finely ground, United States pharmacopeia grade aluminium hydroxide)

Description / Action: 

Phos-clear is for the management of phosphatemia or increased serum phosphorus levels in dogs and cats suffering from chronic kidney disease or CKD. Persistent hyperphosphatemia along with calcitriol deficiency leads to secondary hyperparathyroidism. Phos-clear helps to control hyperphosphatemia by reducing phosphorus absorption from the intestine hence plays its part in controlling the development of secondary hyperparathyroidism.

Calcitriol deficiency leads to negative feedback on the parathyroid gland and persistent hyperphosphatemia leads to hypocalcemia; both result in continuous stimulation of the parathyroid gland and secondary hyperparathyroidism. Secondary hyperparathyroidism leads to metabolic bone diseases, kidney disease, cardiac problems, uremic anemia, reduced carbohydrate metabolism, and immunological response.

Class: Phosphate Binder ⎥ Renal / Kidney Supplement

Indication / Uses:

Phos-clear has Evidence-based Clinical Applications

  • In reducing serum phosphorus level like in CKD
  • In cases of renal secondary hyperparathyroidism

Aluminium hydroxide has advantages over calcium-based phosphorus binders

  • Better phosphorus binding capacity
  • Binds phosphorus in a wider range of gut pH
  • Helps to reduce PTH and Alkaline phosphatase more effectively
  • No additional risk of hypercalcemia and no acceleration of vascular calcification

Phosclear is an ideal choice to start calcitriol therapy in CKD

Dosage and administration:

Phos-clear can be given in dogs and cats @ 2 level scoop / 5 kg per day

Serum phosphorus level                 Phos-clear dosage

6-8 mg/dl                                           100 mg/kg/day

8-10 mg/dl                                         200 mg/kg/day

>10 mg/dl                                          300 mg/kg/day

Route: Oral administration only, Total dose of phosclear must be divided among feedings. Can be mixed/given with the food

Species: Dogs and Cats

Duration: Dogs and cats suffering from chronic kidney disease or chronic kidney failure may need lifelong therapy for effective management of hyperphosphatemia and renal secondary hyperparathyroidism.

Over-dosage / Side effects / Contraindications /Warnings:

In the case of overdosing seek the veterinarian’s advice immediately.

Side-effects, contraindications, and warnings for this nutraceutical product have not been mentioned by the manufacturer. The product supports normal kidney function and reduces serum phosphorus levels in patients suffering from CKD.

Serum phosphorus levels should be checked once in 2 weeks.

Never use without a veterinarian’s advice.

Pharmaceutical precautions / Instructions: 

Store in a cool and dry place at room temperature. Not for use in humans. Strictly for veterinary use. Keep reaching out of the children.

Safety: Age / Pregnancy/ Withdrawal:

Safety for the use in breeding and pregnant animals has not been stated. Age-related instructions have not been mentioned by the manufacturer.

The absorption of the aluminum hydroxide is less than 0.01% hence it is safe. Always follow the recommendations. Withdrawal without consulting may result in the fast progression of CKD and elevated parameters. Always follow your veterinarian’s advice and other medications (exogenous erythropoietin etc) may be needed according to the severity of the CKD and condition of your pet.

Habit-forming:  May need lifelong medication for effective management of phosphatemia in pets suffering from CKD and renal secondary hyperparathyroidism.

Substitute: Vetricare Renal Syrup (Lanthanum carbonate), Ipakitine/Epakitin

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