Description

Biomox Amoxicillin Oral Suspension

Amoxicillin for Dogs

Manufactured by: Virbac AH

Dosage form: Oral Suspension

Presentation: 

Bottle of 15 and 30 ml

Ingredients & Composition:

Each bottle of oral suspension contains

15 ml Suspension        0.75 gm amoxicillin

30 ml Suspension        1.5 gm amoxicillin

When reconstituted, concentration is 50 mg/ml amoxycillin as trihydrate

Inactive Ingredients: Cherry Flavor, Sodium Benozate, Sodium Citrate, Sodium Saccharin, FD&C Red #40, Silicon Dioxide NF, Polyoxyethylene-Polyoxypropylene Glycol, and Sucrose.

Description / Action: 

Biomox oral suspension contains amoxicillin which is a broad-spectrum, semisynthetic antibiotic. It has bactericidal effects on a variety of widespread gram-positive and gram-negative bacteria. Amoxicillin chemically is D-(-) α-amino-p-hydroxybenzyl penicillin trihydrate. Similar to ampicillin, it exhibits bactericidal effect against susceptible organisms.

It works by preventing the bacterial wall mucopeptides’ production. Most strains of the gram-positive and gram-negative bacteria listed below, including nonpenicillinase-producing staphylococci, alpha- and betahemolytic streptococci, Streptococcus faecalis, Escherichia coli, and Proteus mirabilis, have shown amoxicillin susceptibility in both in vitro and in vivo studies.

Amoxicillin is not effective against does not penicillinase-producing bacteria, particularly resistant staphylococci because it does not resist destruction by penicillinase. All strains of Pseudomonas and maximum of Enterobacter and klebsiella strains are resistant.

Stability in gastric acid makes it convenient to give without regard to meals. It is rapidly absorbed and diffuses readily into most body fluids and tissues following oral administration. In case of meningitis, it penetrates CSF and blood brain barrier otherwise diffuses poorly into the brain and spinal fluid. After administration majority of the amoxicillin is excreted in the urine in unchanged form.

Class: Antibiotics (Amino-penicillin)

Indication / Uses:

Indicated in the treatment of the following infections in dogs when caused by susceptible strains of organisms:

1. 1. Bacterial Dermatitis

 Caused by Streptococcus spp.; Staphylococcus aureus, E. coli.

and Staphylococcus spp.

1. 2. Soft Tissue Infections (like abscesses, wounds, lacerations)

Caused by Streptococcus spp.; Proteus mirabilis, Staphylococcus aureus, Staphylococcus spp.; and E. coli.

Like other all antibiotic therapy, appropriate in vitro cultures and sensitivities should be conducted prior to treatment.

Dosage and administration:

The recommended dosage is 5 mg per pound of body weight.

To be administered twice daily for 5 to 7 days.

Don’t discontinue until 48 hours after all symptoms have subsided. If improvement is not noticed in 5 days, the diagnosis should be reconsidered and therapy needs to be changed.

Directions For Mixing Oral Suspension:

Add the recommended quantity of water to the bottle as indicated in the table below and shake vigorously to mix it well. Each mL of reconstituted suspension will contain 50 mg of amoxicillin as the trihydrate.

Bottle Size            Amount of Water to Add for Reconstitution

15 mL                                   11 mL

30 mL                                   21 mL

Species: Oral Use in Dogs Only.

Over-dosage / Side effects / Contraindications /Warnings:

Contraindicated in animals with a known history of an allergic reaction to penicillin.

Amoxicillin is a semisynthetic penicillin and, therefore, has the potential for producing allergic reactions. Epinephrine and/or steroids should be administered if an allergic reaction occurs.

For use in dogs only.

Pharmaceutical precautions / Instructions: 

Keep out of reach of children. Not for human use. Keep this reaching out of the children. Shake well before use after reconstitution. When stored at room temperature or in refrigerator, discard unused portion of reconstituted suspension after 14 days. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Safety: Age / Pregnancy/ Withdrawal:

Instruction regarding safe use in breeding males or pregnant females has not been mentioned by the manufacturer. Until adequate reproductive studies are accomplished, this oral suspension should not be used in pregnant or breeding animals.

Substitute: Toxomox Oral Suspension, Biomox Oral Suspension, Beetapet Oral Suspension,