Description

ATAVON Tablet

Atovaquone Tablets for Dogs and Cats

Manufactured / Marketed by: Sihil Animal Health

Country of Origin: India

Dosage Form: Tablets

Presentation: 

Tablets: 10x1x10 Tablets

Ingredients & Composition:

Each film coated ATAVON Tab contains
Atovaquone USP 250 mg
Excipients          q.s.
Colour: Red oxide of iron

Description / Action: 

Atavon Tablets contain atovaquone which is the drug of Choice for Babesia gibsoni infection in Dogs and Cytauxzoon felis infection in cats.

Pharmacodynamics:

Atovaquone is a highly lipophilic drug that closely resembles the structure of ubiquinone. ATAVON Tab can act by selectively affecting mitochondrial electron transport and parallel processes such as ATP and pyrimidine biosynthesis in Protozoans, especially Babesia gibsoni.

Class: Antiprotozoal

Indication / Usage:

ATAVON Tab is indicated for the treatment of Babesia gibsoni infection in Dogs and Cytauxzoon felis infection in Cats.

Babesiosis in Dogs:

Babesia is a protozoal parasite of mammalian red blood cells and it is an emerging disease in many parts of the world. Natural vectors for B. gibsoni are ixodid ticks and the brown dog tick Rhipicephalus sanguineus. Vertical transmission of B. gibsoni also may occur, as an infection has been found in a dam and her three-day-old pups. Clinical infections are most frequent in young animals.

Cytauxzoon felis in Cats: C. felis is a serious tick-borne protozoal disease of cats.

Dosage/ Administration:

13.4 mg/kg bwt t.i.d. For B. gibsoni and C. felis @ 13.4 mg thrice daily for 10 days in addition to Azithromycin (MACROZEE Tablets) @ 10 mg/kg b.wt once daily for 10 days.

Approximately 250 mg Tab for 20 kg b.wt. is recommended.

For Atovaquone resistant Babesia infection and in case of Mixed infections including E.canis, Anaplasma, B. canis it’s recommended to give Atovaquone@ 13.4 mg/kg and Proguanil 5 mg/kg once daily in addition to Azithromycin @10 mg/kg b wt once for 10 days.

It is also indicated to combine with Imidocarb oral or I/M @ 6.6 mg/kg b.wt on first day and 14th day and Artesunate 12.5 mg/kg b.wt orally for 10 days for Tick fever with most resistant type of Mixed infection with E.canis, Anaplasma, B. canis and B. gibsoni and even other Babesia organisms.

Directions for Use:

Always Give a fatty diet while giving ATAVON to increase the Drug absorption. In case of Azithromycin, it should be given in empty stomach preferably in morning time.

Administer whole do not break or allow to chew.

Targeted Species:

Dogs and Cats

Overdosage / Side effects / Contraindications /Warnings:

Atovaquone has a favourable safety profile and has adverse reactions than other treatments for Babesia gibsoni in Dogs and for Cytauxzoon felis in Cats.

Difficulty in swallowing, Itching, Redness of Skin, Blisters and Loosening of Skin, very rarely fast heartbeat.

Safety/ Pregnancy/ Age:

No specific caution is indicated for the Atovaquone in pregnancy and young animals.

Pharmaceutical precautions / Instructions: 

Keep in a cool dry place at room temperature. Keep away from children. Not for human use. For animal treatment only.

Substitute: Pooch Atova Tablets, Mepron, Malanil, Wellvone, Vaquon Tablets, VETDOX-AQ Tablets & Syrup,