Description

LIV-PURAL Injection

Liver Protective Injection for dogs and cats

Advanced hepatoprotective injectable solution for liver detoxification, ammonia reduction and metabolic recovery across species.

Manufactured/Marketed by: Panav Bio-Tech Pvt. Ltd.

Country of Origin: India

Dosage form: Injectable solution

Presentation:

 10 ml & 50 ml Multiple Dose Vial

Ingredients & Composition:

Ingredient                    Amount

Betaine                        15.0 mg
Arginine HCl              33.3 mg
Ornithine HCl             11.8 mg
Citrulline                     10.0 mg
Sorbitol E420              200.0 mg
Metacresol                   3.0 mg
Water for Injections I.P.       q.s.

Description / Action:

LIV-PURAL Injection is a hepatoprotective injectable solution containing betaine, arginine, ornithine, citrulline and sorbitol for liver disease, hepatic encephalopathy and toxin exposure in dogs, cats and livestock.

Advanced hepatoprotective injectable with 5 synergistic urea-cycle nutrients — supports liver detoxification, ammonia reduction and metabolic recovery across species.

Key Highlights

• US FDA Approved Formula
  Manufactured at WHO-GMP certified facility — internationally validated quality standard.
• Complete Urea Cycle Support
  Ornithine + Citrulline + Arginine together activate the hepatic ammonia detox pathway.
• Flexible Multi-Route Administration
  IM, SC or slow IV — adaptable for clinic and large-animal field use.
• Multi-Species Formulation
  Dogs, cats, cattle, horses, sheep and lambs — a single vial for all species.
• Hepatic Encephalopathy Management
  Reduces ammonia burden critical in HE, post-surgical recovery and toxin exposure.

Class:

Hepatoprotective Injection | Hepatic Detoxification Agent | Urea Cycle Support Therapy

Indication / Uses

• Liver Diseases: Hepatic insufficiency, cirrhosis, fatty liver disease (dogs, cats, cattle).
• Hepatic Encephalopathy (HE): Reduces toxic ammonia buildup through urea cycle activation.
• Toxin Exposure: Aflatoxin, paracetamol, xylitol — supports hepatic detoxification pathways.
• Post-Surgical Recovery: Hepatic support after prolonged anaesthesia or polypharmacy.

Dosage and administration

Dogs and Cats:

• • 2–5 ml according to the body weight or as directed by the registered veterinarian.
  • Refer to the package insert for detailed dosage guidelines based on species.

Route: IM, SC or Slow IV.

Overdoses / Side effects / Contraindications / Warnings

Side effects

• Mild pain or swelling at the injection site
• Transient gastrointestinal upset (rare)
• Hypersensitivity reactions are uncommon
• Temporary restlessness after injection may occur in sensitive animals

Contraindications

• Known hypersensitivity to any component of the formulation.
• Use cautiously in patients with severe electrolyte imbalance or advanced hepatic coma unless specifically indicated.

Warnings

• For veterinary use only.
• Supportive therapy should be combined with treatment of the underlying hepatic disease.
• Monitor liver enzymes, bilirubin and ammonia concentrations during prolonged therapy.
• Maintain adequate hydration in critically ill patients.

Pharmaceutical precautions / Instructions

• Maintain aseptic technique during administration.
• Store in a cool, dry place away from direct sunlight.
• Do not use if the solution appears cloudy or contaminated.
• Keep out of reach of children.

Safety: Age / Pregnancy / Withdrawal

• Age: Suitable for dogs, cats and livestock as directed by the veterinarian.
• Pregnancy/Lactation: Use only after veterinary risk-benefit assessment.
• Withdrawal period: Follow applicable withdrawal recommendations in food-producing animals.

Substitute: LIV-PURAL Tablet,