Description

Nolump Injection

Lithium Antimony Thiomalate Injection

Manufactured/Marketed by:
Manufactured by: Safecon Lifesciences Pvt. Ltd., India.
Marketed by: Wellcon Animal Health Pvt. Ltd. India

Country of Origin: India.

Dosage form: Injection.

Presentation:

Vials of 30 ml, 50 ml & 100 ml. The supplied pack shown is 50 ml.

Ingredients & Composition:

Each ml contains:
Lithium Antimony Thiomalate I.P. (Vet.) — 6% w/v
Chlorocresol I.P. — 1 mg
Water for Injections I.P. — q.s.

The 6% w/v strength corresponds to 60 mg/ml lithium antimony thiomalate.

Description / Action:

Nolump Injection contains Lithium Antimony Thiomalate 6% w/v for veterinary use in papillomatosis, nasal granuloma, filariasis and leishmaniasis in animals.

Lithium Antimony Thiomalate is an organo-antimony compound with antimicrobial, detoxifying, and tissue-restorative properties.

It is especially effective in:

• • Cutaneous warts (Papillomatosis) in cattle & buffalo
  • Nasal granuloma (Chronic nasal growths due to fungal/bacterial infection)
  • It also provides relief in toxaemic conditions, septicemia, and respiratory infections.

Lithium antimony thiomalate is described in veterinary formularies as a trivalent organic antimonial, with its probable therapeutic action in papillomatosis associated with antifibrotic activity.

Class:

Antifibrotic; antimonial preparation; antifilarial/antiprotozoal agent.

The National Veterinary Drug Formulary classifies lithium antimony thiomalate under anti-neoplastic and antifilarial drugs.

Indication / Uses:

Warts (Bovine cutaneous papillomatosis)
Papillomatosis in cattle, buffalo and horses
Nasal granuloma in cattle
Haemorrhagic septicaemia (HS)
Black Quarter (BQ)
Pyaemia
Septicaemia
Pneumonia
Fever
Anorexia
Filariasis in canines
Leishmaniasis in canines
External veterinary references consistently support its use for nasal granuloma, papillomatosis, and canine filariasis/leishmaniasis.

Dosage and administration:

For Nasal Granuloma (Cattle/Buffalo/Horse):
20 ml deep IM route on three occasions at weekly intervals.

For Papillomatosis/Wart (Cattle/Buffalo/Horse):
15 ml deep IM route on 4–6 occasions on alternative days.

Sheep/Goat:
1 ml/25 kg BW deep IM route.

Filariasis and Leishmaniasis in canines:
1 ml to 2.5 ml on 4–6 occasions on alternative days.

Or as directed by the Registered Veterinarian.

The National Veterinary Drug Formulary gives a similar deep-IM regimen, including 20 ml for nasal granuloma and 15 ml for papillomatosis, while veterinary formulary information also lists 1–2.5 ml on alternate days for canine filariasis/leishmaniasis.

Overdoses / Side effects / Contraindications /Warnings:

Overdose:
Avoid overdose, as it can cause toxicity.

Side effects:

Local swelling/pain at injection site
Rare systemic allergic/toxic reaction

Contraindications / Precautions:

Do not use in weak or dehydrated animals.
Avoid overdose.
Use aseptic precautions during injection.
Administer by deep IM route only.
Do not use if the solution is not clear or contains suspended matter.
The supplied pack specifically states that the product is not for human use and is for animal treatment only.

Pharmaceutical precautions / Instructions:

Store in a cool, dry & dark place at a temperature not exceeding 30°C.
Protect from direct sunlight. Keep out of reach of children.
Do not use if solution is not clear or has suspended matter.
For deep I.M. use only. Use aseptic precautions during administration.
The pack specifies not more than ten withdrawals.
The product is to be sold only on prescription of a Registered Veterinary Practitioner.

Safety: Age / Pregnancy/ Withdrawal:

Age: Specific minimum/maximum age is not mentioned.

Pregnancy/Lactation:

A veterinary formulary for lithium antimony thiomalate reports use during pregnancy as safe; this information is generic to the active ingredient and should not be interpreted as a product-specific manufacturer claim.

Withdrawal:

Milk: 7 days after the last administration.

Meat: 28 days after the last administration.

Substitute: Anthiomat Injection, Anthiomaline (Elanco India).