Description

ATIPAMAZ Injection

Atipamezole Hydrochloride injection

Selective alpha-2 adrenergic antagonist for rapid reversal of medetomidine and dexmedetomidine sedation.

Manufactured/Marketed by: Panav Bio-Tech Pvt. Ltd.

Country of Origin: India

Dosage form: Sterile multiple-dose injection

Presentation:

Atipamezole Hydrochloride Injection 5 mg/ml | 10 ml Sterile Multiple Dose Vial

Ingredients & Composition:

Ingredient / Active Substance                Amount / Strength
Atipamezole Hydrochloride                  5 mg per ml (50 mg/10 ml)
Excipients                                              q.s.

Description / Action:

ATIPAMAZ Injection contains Atipamezole Hydrochloride 5 mg/ml for rapid reversal of medetomidine and dexmedetomidine sedation in dogs, cats and wildlife. Selective alpha-2 antagonist for veterinary emergency medicine.

The ultimate selective alpha-2 adrenergic antagonist — rapid, complete reversal of medetomidine and dexmedetomidine sedation in small animals and wildlife.

Key Highlights

• • Fast & Reliable Reversal
    Rapidly counteracts sedation, restoring normal behaviour and mobility within minutes.
  • Precise Selective Action
    Specifically antagonises alpha-2 agonists without affecting other receptors.
  • Safe for Small Animals & Wildlife
    Ideal for dogs, cats, zoo animals, and exotic species — wide margin of safety.
  • Reduced Recovery Time
    Minimises post-anaesthetic stress and complications, enhancing patient wellbeing.
  • Field-Ready for Wildlife
    Ensures quick revival in remote conditions, reducing handling time and stress.

Class:

Selective Alpha-2 Adrenergic Receptor Antagonist | Sedation Reversal Agent | Emergency Medicine

Indication / Uses

• Reversal of Medetomidine Sedation: Complete antagonism of sedation in dogs and cats post-procedure.
• Reversal of Dexmedetomidine Sedation: Post-surgical and post-procedural recovery support.
• Wildlife Immobilisation Recovery: Recovery facilitation following alpha-2 immobilisation of zoo and wild animals.
• Zoological & Conservation Settings: Safe and effective for post-procedural management in field conditions.

Dosage and administration

10 ml vial (5 mg/ml concentration) of Atipamezole Hydrochloride Injection.

Refer to the package insert for detailed dosage guidelines based on species and sedation depth.

Overdoses / Side effects / Contraindications / Warnings

Side effects

• • Transient excitement or hyperactivity
  • Tachycardia
  • Muscle tremors
  • Vomiting (occasionally)
  • Increased salivation
  • Rare hypotension or arrhythmias following inappropriate dosing

Contraindications

• • Do not administer to animals that have not received medetomidine or dexmedetomidine.
  • Hypersensitivity to atipamezole.
  • Use cautiously in animals with severe cardiovascular disease.

Warnings

• • Administer only after completion of the required procedure.
  • Recovery should be monitored until the animal regains normal physiological function.
  • Rapid reversal may unmask pain previously controlled by alpha-2 agonists.
  • Use only under veterinary supervision.

Pharmaceutical precautions / Instructions

For veterinary use only. Maintain aseptic technique while withdrawing doses.

Store in a cool, dry place protected from direct sunlight.

Keep out of reach of children.

Safety: Age / Pregnancy / Withdrawal

Age: Suitable for dogs, cats and wildlife species receiving alpha-2 agonists as recommended by the veterinarian.

Pregnancy/Lactation: Safety has not been fully established; use only after veterinarian risk-benefit assessment.

Withdrawal period: Follow applicable veterinary regulations in food-producing animals.

Substitute: Antisedan (Atipamezole Hydrochloride) Injection,