Description

YOHIMAX Injection

Xylazine antidote for reversal

Selective alpha-2 antagonist injection for rapid reversal of xylazine sedation in veterinary patients.

Manufactured/Marketed by: Panav Bio-Tech Pvt. Ltd.

Country of Origin: India

Dosage form: Sterile multiple-dose injection

Presentation:

Yohimbine Hydrochloride Injection 10 mg/ml | 10 ml Sterile Multiple Dose Vial

Ingredients & Composition:

Ingredient                                                        Strength
Yohimbine (as Hydrochloride) BP (Active)   10 mg per ml
Methyl Paraben I.P. (Preservative)                 0.9 mg per ml
Propyl Paraben I.P. (Preservative)                  0.1 mg per ml
Citric Acid I.P. (Buffer)                                  3.34 mg per ml
Water for Injections I.P.                                  q.s.

Description / Action:

YOHIMAX Injection contains Yohimbine Hydrochloride for rapid reversal of xylazine sedation in dogs, cats, horses and wildlife. Fast alpha-2 antagonist for veterinary emergency medicine.

First in India to reverse xylazine effects — selective alpha-2 antagonist for rapid anaesthetic recovery in dogs, cats, horses, deer, antelopes and elephants.

Key Highlights

• • First in India — Xylazine Reversal
    Pioneer alpha-2 antagonist for xylazine reversal introduced to the Indian veterinary market.
  • Rapid Recovery Induction
    Reverses sedation, analgesia and bradycardia induced by xylazine within minutes.
  • Multi-Species Scope
    Sport horses, dogs, cats, deer, elk, antelopes and elephants — one product for diverse practice.
  • Precise Low-Dose Efficacy
    Effective at 0.125–0.25 mg/kg — minimal dose for maximum reversal effect.
  • Field-Ready Formulation
    Sterile multiple dose vial — practical for wildlife capture and field anaesthesia.

Class:

Alpha-2 adrenergic receptor antagonist | Xylazine reversal agent | Emergency medicine

Indication / Uses

• Xylazine Sedation Reversal: Dogs, cats, horses and large animals following xylazine administration.
• Wildlife Capture Recovery: Deer, elk, antelopes — rapid post-immobilisation revival for release.
• Elephant Anaesthesia Recovery: Approved for large wildlife reversal protocols under specialist supervision.
• Emergency Xylazine Overdose: Reversal of toxic xylazine effects to restore normal cardiovascular function.

Dosage and administration

Overdoses / Side effects / Contraindications / Warnings

Side effects

• • Tachycardia
  • Excitement or restlessness
  • Muscle tremors
  • Increased salivation
  • Transient hypertension
  • Rare arrhythmias with excessive dosage

Contraindications

• • Do not administer unless xylazine has been used.
  • Use cautiously in animals with severe cardiovascular disease.
  • Hypersensitivity to yohimbine hydrochloride.

Warnings

• • Rapid administration may produce excessive CNS stimulation.
  • Continuous monitoring of heart rate, respiration and blood pressure is recommended during recovery.
  • Use only under veterinary supervision.
  • Dose should be adjusted according to the degree of sedation and patient response.

Pharmaceutical precautions / Instructions

For veterinary use only. Maintain aseptic technique during withdrawal.

Store in a cool, dry place away from direct sunlight. Keep out of reach of children.

Safety: Age / Pregnancy / Withdrawal

Age: Suitable for veterinary patients receiving xylazine as recommended by the veterinarian.

Pregnancy/Lactation: Use only after veterinarian assessment of benefits and risks.

Withdrawal period: Follow applicable veterinary regulations in food-producing animals.

Substitute: Updating Soon,