Description

Vet Thyro Tablets

Levothyroxine Sodium 0.2 mg & 0.6 mg

Levothyroxine Sodium for Dogs

Levothyroxine Sodium for Cats

The Established Cost-Effective Treatment for Hypothyroidism

Manufactured by: Vivaldis Animal Health

Dosage form: Tablets

Presentation: 

A box containing to strips of 30 tablets each

Ingredients & Composition:

Each film coated tablet contains

Levothyroxine sodium IP
Equivalent to anhydrous levothyroxine sodium               0.2 mg or 0.6 mg
Excipients                   q.s.
Colour:      Red oxide iron

Description / Action: 

Vet Thyro Tablets contain levothyroxine sodium for dogs and cats. Levothyroxine restores adequate thyroid hormone concentration, reversing hypothyroidism.

Mechanism of action of Levothyroxine

Levothyroxine is converted to hormone T3 which binds to thyroid receptor proteins and carries out the following functions:
• Controls DNA transcription & stimulates protein synthesis, exerting metabolic effects
• Increases basal metabolic rate
• Increases utilisation and mobilisation of glycogen stores
• Promotes gluconeogenesis

Class: Hormones/ Thyroxin/ Levothyroxine

Indication / Uses:

• For Treatment of hypothyroidism in dogs and cats

Clinical signs of hypothyroidism
• Decreased metabolism
• Weight gain without corresponding increase in appetite
• Lethargy, laziness
• Weakness, exercise intolerance
• Cold intolerance
• Slow heart rate
• Skin & coat problems
• Chronic skin infections
• Ear infections
• Alopecia
• Hyperpigmentation
• Hyperkeratosis
• Dry, dull haircoat
• Seborrhoea

Diagnosis of Hypothyroidism

Reference Values for Hypothyroidism in Dogs and Cats

Diagnostic test            Canine                         Feline
Total T4                      1.0-4.0 µg/dL              0.8-4.7 µg/dL
TSH                            0.0-0.5 ng/ml              0.0-0.3 ng/ml

Criteria for confirmation of hypothyroidism = LOW Total T4+ HIGH TSH + clinical signs

Delayed diagnosis or untreated hypothyroidism may lead to
• Slow heart rate, weak apex beat,
• Weak pulse and low voltage on ECG
• Hypercholesterolemia
• Elevated serum creatinine
• Normochromic, normocytic anaemia
• Head tilt, disturbed/unsteady gait, facial paralysis

Treatment of hypothyroidism
• Daily oral administration of synthetic thyroid hormone Levothyroxine (LT4)
• Treatment for hypothyroidism is lifelong
• Levothyroxine is effective and safe and will improve the quality of life

Dosage and administration:

Dogs & Cats: 0.02-0.04 mg/kg/day
Dose can be given once or in two divided doses
Administration should be at least 1 hour prior to feeding

Dose adjustment:

Test: Total T4 (4 weeks after starting Lt 4)

High Total T4 (>6 µg/dL)            Dose to be decreased by 25%
Normal Total T4 (4-6 µg/dl)        Dose correction not required
Low Total T4 (<4 µg/dL)             Dose to be increased by 25%

Once an effective dose has been established, the interval between monitoring visits is increased to every 6 months

Route: Oral administration only.

Species: In Dogs and Cats.

Duration: For the management of hypothyroidism lifelong supplementation will be needed.

Over-dosage / Side effects / Contraindications /Warnings:

Signs of over dosing (if observed before repeat test, dose can be adjusted accordingly)
• Excessive weight loss
• Hyperactivity
• Irritability
• Increased thirst and/or increased panting
• Lack of sleep.

Never use without veterinarian’s advice.

Pharmaceutical precautions / Instructions: 

Store in a cool and dry place at room temperature. Not for use in humans. Strictly for veterinary use. Keep reach out of the animals and children.

Not to be sold in retail without a prescription of a registered veterinary practitioner.

Safety: Age / Pregnancy/ Withdrawal:

Safe for use in young/ adult/ aged cats and dogs.

 Substitute: Updating soon