Description

L-Sametine Syrup

Supports Neuronal Development & Functioning

Revitalise Neurons

Manufactured by: Vivaldis Animal Health

Dosage form: Syrup

Presentation: 

A bottle containing 200 ml

Ingredients & Composition:

(Active ingredients per 5 ml)

Methylcobalamin                 500 μg
S-Adenosyl methionine       90 mg
Omega 3 Fatty Acids           500 mg
Vitamin B1                           3 mg
Vitamin B6                           3 mg
Folic acid                             150 µg
L-carnitine                           150 mg
Selenium                              75 µg
Magnesium oxide                30 mg
Palatable Chicken Flavour

Description / Action: 

L-Sametine Syrup is a supplement to support neuronal function and prevents progressive loss of neuronal function in dogs and cats. It is helpful in the treatment of anxiety, aggression, epilepsy and cognitive dysfunction in dogs and cats.

Neurodegeneration

Neurodegeneration is the progressive loss of neuronal structure and function, resulting in cell death.
Factors like Neuroinflammation, Synapse degeneration, Axon transport dysfunction, Apoptosis, Excitotoxicity, and Defective neuro-development causes Neuronal dysfunction and Neuronal disorders.
This dysfunction/ disorder is manifested as
• Aggression
• Behavioural disorders
• Movement disorders
• Epilepsy
• Travel stress /anxiety

Diagnosis of various nervous disorders
Diagnosis can be made based on the presence of one or more of the following “DISHAAL” signs which other medical conditions cannot explain:
• Disorientation
• Interaction changes
• Sleep cycle changes
• House soiling
• Activity level changes
• Anxiety
• Learning/ memory changes

Mode of Action:

Epilepsy –
Omega 3 fatty acids, Folic acid & BV 3 Vitamins
• Glutamate accumulation in the synapses leads to excitotoxicity and epileptic seizures.
• Improves glutamate transportation which reduces frequency and intensity of seizures.
• Controls cytokines which are responsible for seizures
•Modulation of proinflammatory markers like CRP, TNFα, IL-10, TGFα
• Normalises Folic acid levels to reduce seizures
• Improves metabolism and maintenance in neurons
• Overcomes neurological disorders associated with Vit. B deficiency

Neurotransmission issues –
SAME, Methylcobalamin, Folic acid & L-Carnitine
• Improves neurotransmitter synthesis
• Improves neuronal communication
• Improves functioning of nervous system
• Modulates neurotransmitter transduction pathways

Decline in neuronal development and/or function
SAME, Methylcobalamin, Folic acid, Omega 3 fatty acids and vitamins
• Protects against decline in function caused due to free radical damage
• Overcomes cognitive dysfunction, impaired memory loss and mental alertness by correcting Methylcobalamin levels
• Overcomes cognitive decline, depression, epilepsy by correcting folic acid levels
• Improves neuronal development and function
• Improves synapse regeneration
• Regulates maintenance and metabolism in neurons
• Imparts cognitive development

Inflammation, Oxidative stress, Neuronal damage and Apoptosis
SAME, Omega 3 fatty acids & L-Carnitine
• Improves intracellular glutathione levels
• Potent anti-inflammatory effects
• Promotes neuroprotective metabolites in CNS
• Improves mitochondrial dysfunction, lowers neuronal apoptosis

Combined effect of SAMe, methylcobalamin and folic acid
• Facilitates the production of tetrahydrofolate, Phosphatidylcholine, myelin, melatonin, catecholamines, DNA, and RNA
• Supplementation of SAMe, methylcobalamin and folic acid leads to improvement in the transmethylation cycle which corrects neurodegenerative disorders.

Class: Supplement

Indication / Uses:

• Epilepsy
• Aggression Behavioural disorders
• Anxiety (travel, separation)
• Movement disorders
• Cognitive decline

Features

• Unique combination of S-Adenosyl methionine, L-carnitine, Methylcobalamin and Folic acid
• Improves neuronal stability and function
• Protects neurons from damage and slows neuronal degeneration
• Liquid formulation provides ease of administration

Dosage and administration:

1 ml per 5 kg twice a day
As directed by or recommended by your veterinarian.

Route: For oral administration only

Species: Dogs and Cats

Over-dosage / Side effects / Contraindications /Warnings:

An examination from a veterinarian is recommended before using the product. In case of accidental overdose contact a veterinarian immediately.

Pharmaceutical precautions / Instructions: 

Store in a cool dry place away from direct sunlight. Keep out of reach of children and animals.

Safety: Age / Pregnancy/ Withdrawal:

Safe use in pregnant pets has not been proven.

Substitute: Updating soon

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